Afiqah Yaacob, Nor Hafizah Ngajikin, Nurfatihah Che Abd Rashid, Siti Hajar Aminah Ali, Maslina Yaacob, Nurfarina. Zainal, Ian Yulianti, Noran Azizan Cholan
This study demonstrates a wide linearity range for uric acid sensing in the visible and near-infrared spectrum using direct spectroscopy detection, eliminating the need for enzymes or reagents. The system was experimentally tested across a uric acid concentration range of 10 to 200 mg/dL, exhibiting excellent performance in linearity, sensitivity, and accuracy, with optimal results observed at a wavelength of 950 nm. At this wavelength, the sensor achieved a linearity of 0.9694, sensitivity of 0.0034 (mg/dL)^-1, and accuracy of 97.42%. Compared to the previous developments, this work validates the improved linearity range performance and offers rapid response times due to its reagent-free design. The proposed sensor shows strong potential for efficient real-time monitoring of uric acid over a wide concentration range. This is an open access article under the CC BY-NC-SA 4.0 license.
Faculty of Electrical and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, Johor, Batu Pahat, 86400, Malaysia; Department of Physics, Universitas Negeri Semarang, Semarang, 50229, Indonesia
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