Rifky Ismail, Deni Fajar Fitriyana, Athanasius Priharyoto Bayuseno, Jamari, Putut Yoga Pradiptya, Rilo Chandra Muhamadin, Fariz Wisda Nugraha, Rusiyanto, Andri Setiyawan, Aldias Bahatmaka, Hendrix Noviyanto Firmansyah, Samsudin Anis, Agustinus Purna Irawan, Januar Parlaungan Siregar, Tezara Cionita
Chitosan has been broadly utilized in bone scaffold production because of its antibacterial qualities, low toxicity, biodegradability, biocompatibility, and ability to aid regeneration processes in wound healing. In this work, chitosan was produced from crab shell waste through demineralization, deproteination, and deacetylation, utilizing HCl 1:7 (v/v), NaOH 3%, 1:10 (v/w), and NaOH 50%. The aim of this study is to examine the deacetylation temperature’s impact towards the crystallinity index, chemical bond, degree of deacetylation, and morphology of chitosan synthesized. The deacetylation procedure was conducted for eight hours at temperatures of 100°C, 120°C, and 140°C. The synthesized chitosan was evaluated by utilizing XRD, FTIR, and SEM methods. According to the findings of this investigation, deacetylation at a temperature of 140 °C produced the highest degree of deacetylation, resulting in the highest quality chitosan. In addition, compared to other obtained chitosans, the shape of this result of synthesis is homogenous. At a deacetylation temperature of 140°C, the amounts of deacetylation degree, and crystallinity index of the chitosan were, in order, 81%, and 44% © 2023, Journal of Advanced Research in Fluid Mechanics and Thermal Sciences.All Rights Reserved.
Mechanical Engineering Dept., Diponegoro University, Semarang, Indonesia; Center for Biomechanics, Biomaterial, Biomechatronics, and Biosignal Processing, Diponegoro University, Semarang, Indonesia; Mechanical Engineering Dept., Universitas Negeri Semarang, Semarang, Indonesia; Faculty of Engineering, Universitas Tarumanagara, Jakarta Barat, 11440, Indonesia; Colleges of Engineering, Universiti Malaysia Pahang, Gambang,Kuantan, 26300, Malaysia; Department of Mechanical Engineering, Faculty of Engineering and Quantity Surveying, INTI International University, Negeri Sembilan, Nilai, 71800, Malaysia
